Overlooking the River Nile, Hilton Nile is next to the Egyptian Museum, eight miles from the Pyramids, and approximately 13 miles from Cairo International Airport. Transportation from the airport is available by taxi or limo service (fees apply). This location is also adjacent to the Egyptian Museum and rides on the Nile, half a mile from Cairo Tower, five miles from the Citadel & Mohamed Ali Mosque, six miles from Coptic Hanging Church & Coptic Museum, eight miles from the Sphinx, and nine miles from the Sakkara Step Pyramid.

Hotel amenities include the two tennis courts, health club, sauna and steam room, massage treatments, outdoor pool, sun deck and loungers, cabanas, poolside bar, and 10 bars and restaurants. Room service is available 24 hours. Wireless Internet access is available in public areas. The hotel also offers 10 meeting and conference rooms, a business center, concierge assistance, laundry facilities, dry cleaning, currency exchange, parking (fee applies), and 24-hour front desk service.

All rooms feature air-conditioning, wireless Internet access, direct-dial phones, desks, complimentary toiletries, and balconies with views over Cairo or the Nile. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.