Set at the foot of the Andes Mountains, Marriott Santiago is situated within the Las Condes business district and approximately 12 miles from Arturo Merino Benitez Airport. The hotel is a block from the Parque Arauco Shopping Mall, two miles from Club de Golf Los Leones, four miles from Cerro San Cristobal, five miles from the Museum of National History, and eight miles from downtown Santiago.

Hotel amenities include the gift shop, barber/beauty salon, indoor/outdoor heated pool, children's pool, hot tub, health club and spa, lap pool, steam room, Cafe Med, Latin Grill, Cordillera Lounge, and Pool Bar Lounge. Room service is available 24 hours. The hotel also offers concierge assistance, babysitting, turndown service, laundry facilities, grocery shopping service, and free parking.

All rooms feature high-speed Internet access, cable TV, dual-line telephones, voicemail, clock radios, coffeemakers, individual climate control, irons and ironing boards, safes, bathrobes, hairdryers, and minibars. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.