The Hotel Sante Fe is situated on a private beach on Agana Bay, approximately three miles from Ypao Beach Park and six miles from Guam International Airport. This rose-colored, adobe-style boutique hotel reflects Guam's warm and inviting Spanish heritage.

Hotel amenities include the infinity-edge pool and sundeck, Jacuzzi, and Grille at Santa Fe, an open-air restaurant and bar. The hotel also offers a business center, banquet room, wireless Internet access, free parking, 24-hour front desk service, 24-hour security, coin-operated laundry facilities, and laundry service.

Guest rooms feature air-conditioning, cable TV, blackout drapes, safes, coffeemakers, hairdryers, complimentary toiletries, and mini-refrigerators, and garden, mountain, or Pacific Ocean views. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.