The Hotel Amarano Burbank is located in the Burbank Media District, approximately two miles from Universal City and Burbank International Airport. It is within walking distance to Warner Brothers, NBC, Disney, and major production facilities.

There is a health facility with hot tub on the landscaped rooftop. The hotel also has a full-service bar, 24-hour room service, High Tea, complimentary transportation to the studios, and complimentary high-speed Internet access.

All rooms have Italian linens, duvets, three dual-line phones, voicemail, safes, DVD and CD players, fax machine (on request), mini-refrigerators, coffeemakers, marble bathrooms, armoires, and work/dining areas. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.