The Holiday Inn Express is located in the heart of Sanford and adjacent to the Sagebrush Steakhouse and Saloon. It is close to all major industry in Lee County including, Coty, Caterpillar, GKN, General Shale, Wyeth, Static Control, Magneti Marelli, and Moen. Other attractions include the Pottery stores, Coty Outlet and Temple Theatre.

There is wireless HSIA throughout the entire hotel. The amenities include a health and fitness center, housekeeping and laundry service, business service, and high-speed Internet access.

The property offers a microwave and refrigerator in every guest room. All the rooms include a personal safe and feature the new Serta Concierge Mattress in every room. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.