The Holiday Inn Express Portsmouth is conveniently accessible to US-23N, approximately four miles from downtown Portsmouth, 91 miles from Port Columbus International Airport, and 120 miles from Cincinnati Northern Kentucky International Airport. Local attractions include Shawnee State University, Clark Planetarium, Roy Rogers Esplanade, and Tracy Park.

Hotel amenities include complimentary breakfast, free parking, fax/photocopying services, laundry/dry cleaning, ice machine, free local telephone calls, and safe deposit box. Guests may also enjoy the indoor pool, newsstand, business center, and guest laundry facilities.

Guest rooms feature satellite/cable TVs, hairdryers, high-speed Internet access, individual climate controls, irons, ironing boards, coffeemakers, in-room movies, microwaves, refrigerators, dual-line telephones, voicemail, and work desks with lamps.
Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.