Holiday Inn Express Henderson is located two miles from downtown Henderson, nine miles from Kerr Lake, 10 miles from Oxford, and approximately 50 miles from Raleigh-Durham International Airport. This location is also eight miles from Henderson, 35 miles from South Hill, 45 miles from Durham, and 50 miles from Raleigh.

The property's amenities include the exercise room and complimentary continental breakfast. The hotel also offers valet laundry service and free parking.

All rooms feature dual-line phones, free high-speed Internet access, voicemail, microwaves, refrigerators, coffeemakers, irons and ironing boards, hairdryers, and cable TV. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.