Holiday Inn Express Durham is located approximately half a mile from the University of New Hampshire, five miles from Fox Run Mall, and 35 miles from Manchester Airport. This location is also three miles from Hilton Park and Wagon Hill, five miles from the Redhook Brewery, eight miles from the Kittery Outlets, and 15 miles from Hampton Beach.

Hotel amenities include the complimentary buffet breakfast. The hotel also offers laundry facilities, dry cleaning, free weekday newspapers, and free parking. Small pets are allowed (fees or hotel approval may apply).

All rooms feature cable TV, in-room movies, coffeemakers, high-speed Internet access, voicemail, irons and ironing boards, and hairdryers. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.