Located along Huan Shi Dong in the city's commercial center, Holiday Inn City Centre Guangzhou is approximately 20 miles from New Baiyun International Airport. This location is also half a mile from the World Trade Center and Guangzhou Friendship Store, three miles from Baiyun Mountain and Sun Yat-Sen Memorial Hall, five miles from the Chen Clan Temple and Guang Xiao Temple, 10 miles from Big Hippo Water World, and 13 miles from the Chime-Long Night Zoo, Guangzhou Grand World Scenic Park, and Xiangjiang Safari Park.

Hotel amenities include the health club, swimming pool, sauna, beauty salon, gift shop, business center, Cafe Cascade (buffet restaurant), Dai Pai Dong (dim sum, noodles, etc), Oscar's Italian Restaurant, and Inn Bar. The hotel also offers room service, valet laundry service, a concierge, currency exchange, babysitting, and parking (fee).

All rooms feature satellite TV, in-room movies, coffeemakers, minibars, safes, hairdryers, high-speed Internet access, free local calls, individual climate controls, irons and ironing boards, voicemail, and work desks. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.