Hilton Sheffield is located on the historic Victoria Quays, half a mile from the city center shops and attractions, and approximately two miles from Sheffield Airport. This location is also five blocks from the Millennium Galleries and Winter Gardens, two miles from the Magna Science Adventure Centre, 13 miles from Bolsover Castle, and 20 miles from Chatsworth House and Gardens and Peak District National Park.

Hotel amenities include the spa center's beauty treatments, aromatherapy, and massage therapists. The health club offers more than 60 fitness classes a week, alongside holistic treatments, a gym, an indoor pool, and a sauna. Sheffield Hilton Restaurant serves contemporary British cuisine, Caffe Cino is a coffee bar with snacks and sandwiches, and Bar Bacoa Bar has a variety of light meals and snacks. Room service is available around the clock. The hotel also offers a complimentary breakfast each morning, concierge assistance, laundry facilities, nine meeting and conference rooms, a business center, wireless Internet access, parking for 80 cars (fee applies), and 24-hour front desk service.

All rooms feature power showers, tea and coffee facilities, trouser presses, hairdryers, complimentary toiletries, high-speed Internet access, voicemail, and desks. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.