The Hampton Inn and Suites Mobile - Downtown Historic District is centrally located in Mobile; this property is near Gulf Coast Exploreum, Museum of Mobile, and Bienville Square. Another attraction in the area includes Christ Church Cathedral.

This property offers amenities like a complimentary hot and cold buffet breakfast which is served each morning. The amenities at the property include an outdoor pool and a fitness facility. Business-related amenities include complimentary wireless Internet access and a business center. Meeting facilities include conference rooms and meeting rooms for small groups. The property also offers laundry facilities and dry cleaning service, outdoor swimming pool, safe-deposit box, and a front desk.

The property has 150 guest rooms, which feature air-conditioning, cable TV, clock radios, refrigerators, microwaves, and coffee or tea makers. Bathrooms include hairdryers and handheld showers. The hotel is wheelchair accessible. Business-friendly rooms are equipped with complimentary wireless Internet access and desks. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.