Express by Holiday Inn Salford Quays is located approximately a quarter-mile from the Salford Quays Watersports Centre and 14 miles from Manchester International Airport. Salford Quays is a busy business and leisure district surrounded by the water of Manchester's Ship Canal. This location is also half a mile from the Salford Quays Tram Stop and Old Trafford Cricket Ground, one mile from the Manchester United Football Ground and Museum and Imperial War Museum, two miles from Manchester Evening News Arena and Manchester Town Hall, three miles from Trafford Centre Shopping, four miles from Manchester's Curry Mile, and five miles from Manchester Commonwealth Games Stadium.

The property has 120 spacious, well equipped bedrooms all featuring satellite TV, in-room movies, coffee/tea facilities, and hairdryers. Amenities include the licensed bar and complimentary continental breakfast. The hotel also offers meeting facilities, valet laundry service and free parking. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.