Holiday Inn San Pedro Sula is located half a mile from the cathedral and anthropology museum and approximately 10 miles from Ramon Villeda Morales Airport. This location is also one mile from Maya World, three miles from the Olympic Village, and 155 miles from Tegucicalpa and Bahia Island.

Hotel amenities include the swimming pool, fitness room, business center, Rio de Piedras (24-hour coffee shop), and Cerro de Plata (cocktail lounge). The hotel also offers room service, concierge assistance, valet laundry service, laundry facilities, and free parking.

All rooms feature satellite TV, in-room movies, coffeemakers, hairdryers, individual climate control, irons and ironing boards, voicemail, and work desks. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.