The Crowne Plaza Panama is four miles from the Panama Canal and approximately 12 miles from Tocumen International Airport. This location is also two miles from the Multiplaza Shopping Center and Casco Antiguo (historical monuments), three miles from the Atlapa Convention Center and Panama La Vieja (Old Panama ruins), five miles from the Miraflores Locks, 28 miles from Barro Colorado Island, 50 miles from Portobello, and 60 miles from El Valle de Anton.

Hotel amenities include the outdoor pool, fitness room, shopping gallery, business center, Internet cafe, La Galeria Restaurant (fine international and regional cuisine), and Memories Sports Bar (honoring Panamanian sports heroes). The hotel also offers 24-hour room service, indoor parking, babysitting, concierge services, laundry services, safety deposit, and a tour desk.

All rooms feature air-conditioning, clock radios, bathrobes, bath amenities, hairdryers, irons and ironing boards, minibars, voicemail, dataports, coffeemakers, and cable TV. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.