Comfort Inn Boonville is located at the junction of I-70 and State Highway 5, three miles from the Isle of Capri Casino and Katy Trail, and approximately 45 miles from Columbia Regional Airport. This location is also five miles from the Hain House, 15 miles from Ravenswood and Boonslick State Park, 25 miles from the Columbia Shopping Mall, and 50 miles from the Missouri State Fair.

Hotel amenities include the indoor pool, whirlpool, and complimentary continental breakfast.

All rooms feature free local calls, free high-speed Internet access, alarm clocks, hairdryers, irons and ironing boards, coffeemakers, and cable TV. Microwaves and refrigerators may be available upon request. Rates are based on double occupancy. Charges for extra adults may apply and will be due directly to the hotel.